VCU News: New Insights into Cancer Genetics Through Cell Interactions

The article from VCU News, published on November 16, 2023, highlights groundbreaking research conducted by Virginia Commonwealth University and the University of Copenhagen. The study, led by Dr. Rajan Gogna and others, delves into how physical contact between cells influences genetic changes and gene expression. This research, published in the Proceedings of the National Academy of Sciences and Molecular Systems Biology, is pivotal in understanding cancer development. It focuses on how cancer and normal cells affect each other, impacting tumor growth and response to therapies. This novel approach, combining RNA sequencing and AI, helps in understanding the genetic signatures linked to neighboring cell interactions, which is crucial in fighting cancer and could potentially explain racial disparities in cancer susceptibility and survival.

For a more detailed exploration, you can read the full article on Medical Xpress or check the VCU Massey Comprehensive Cancer Center website for related research insights.

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Gogna lab was awarded funding from the Adenoid Cystic Carcinoma Research Foundation (ACCRF)

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